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Differential regulation of p53 target genes: it's (core promoter) elementary

p53 is a pleiotropic transcription factor driving a flexible transcriptional program that mediates disparate cellular responses to stress, including cell cycle arrest and apoptosis. The mechanisms by which p53 differentially regulates its diverse target genes remain poorly understood. In this issue...

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Bibliografiske detaljer
Main Authors: Gomes, Nathan P., Espinosa, Joaquín M.
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2807345/
https://ncbi.nlm.nih.gov/pubmed/20080948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1893610
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