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Targeting HAUSP in both p53 wildtype and p53-mutant tumors
Inhibition of Mdm2 function is a validated approach to restore p53 activity for cancer therapy; nevertheless, inhibitors of Mdm2 such as Nutlin-3 have certain limitations, suggesting that additional targets in this pathway need to be further elucidated. Our finding that the Herpesvirus-Associated Ub...
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| Publicado en: | Cell Cycle |
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| Autores principales: | , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Taylor & Francis
2018
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6056219/ https://ncbi.nlm.nih.gov/pubmed/29616860 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2018.1456293 |
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