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Polo inhibits progenitor self-renewal and regulates Numb asymmetry by phosphorylating Pon
Self-renewal and differentiation are cardinal features of stem cells. Asymmetric cell division provides one fundamental mechanism by which stem cell self-renewal and differentiation are balanced1,2. A failure of this balance could lead to diseases such as cancer3–6. During asymmetric division of ste...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3047501/ https://ncbi.nlm.nih.gov/pubmed/17805297 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature06056 |
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