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Dronc caspase exerts a non-apoptotic function to restrain phospho-Numb-induced ectopic neuroblast formation in Drosophila

Drosophila neuroblasts have served as a model to understand how the balance of stem cell self-renewal versus differentiation is achieved. Drosophila Numb protein regulates this process through its preferential segregation into the differentiating daughter cell. How Numb restricts the proliferation a...

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Detalhes bibliográficos
Main Authors: Ouyang, Yingshi, Petritsch, Claudia, Wen, Hong, Jan, Lily, Jan, Yuh Nung, Lu, Bingwei
Formato: Artigo
Idioma:Inglês
Publicado em: Company of Biologists 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3091490/
https://ncbi.nlm.nih.gov/pubmed/21558368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.058347
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