Precardiac deletion of Numb and Numblike reveals renewal of cardiac progenitors

Cardiac progenitor cells (CPCs) must control their number and fate to sustain the rapid heart growth during development, yet the intrinsic factors and environment governing these processes remain unclear. Here, we show that deletion of the ancient cell-fate regulator Numb (Nb) and its homologue Numb...

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Hlavní autoři: Shenje, Lincoln T, Andersen, Peter, Uosaki, Hideki, Fernandez, Laviel, Rainer, Peter P, Cho, Gun-sik, Lee, Dong-ik, Zhong, Weimin, Harvey, Richard P, Kass, David A, Kwon, Chulan
Médium: Artigo
Jazyk:Inglês
Vydáno: eLife Sciences Publications, Ltd 2014
Témata:
Developmental Biology and Stem Cells
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4007206/
https://ncbi.nlm.nih.gov/pubmed/24843018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.02164
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