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Non-Canonical Notch Signaling: Emerging Role and Mechanism

Notch is an ancient transmembrane receptor with critical roles in cell-fate choices. While the “canonical” Notch pathway and its core members are well established -- involving ligand-induced cleavage of Notch for transcriptional regulation -- it has been unclear whether Notch can also function indep...

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Detalhes bibliográficos
Main Authors: Andersen, Peter, Uosaki, Hideki, Shenje, Lincoln, Kwon, Chulan
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3348455/
https://ncbi.nlm.nih.gov/pubmed/22397947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tcb.2012.02.003
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