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Aurora-A acts as a tumor suppressor and regulates self-renewal of Drosophila neuroblasts

The choice of self-renewal versus differentiation is a fundamental issue in stem cell and cancer biology. Neural progenitors of the Drosophila post-embryonic brain, larval neuroblasts (NBs), divide asymmetrically in a stem cell-like fashion to generate a self-renewing NB and a Ganglion Mother Cell (...

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Detalhes bibliográficos
Main Authors: Wang, Hongyan, Somers, Gregory W., Bashirullah, Arash, Heberlein, Ulrike, Yu, Fengwei, Chia, William
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1698451/
https://ncbi.nlm.nih.gov/pubmed/17182870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1487506
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