Caricamento...

Inhibition of NADPH oxidase by glucosylceramide confers chemoresistance

The bioactive sphingolipid ceramide induces oxidative stress by disrupting mitochondrial function and stimulating NADPH oxidase (NOX) activity, both implicated in cell death mechanisms. Many anticancer chemotherapeutics (anthracyclines, Vinca alkaloids, paclitaxel and fenretinide), as well as physio...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Barth, Brian M, Gustafson, Sally J, Young, Megan M, Fox, Todd E, Shanmugavelandy, Sriram S, Kaiser, James M, Cabot, Myles C, Kester, Mark, Kuhn, Thomas B
Natura: Artigo
Lingua:Inglês
Pubblicazione: Landes Bioscience 2010
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3047104/
https://ncbi.nlm.nih.gov/pubmed/20935456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.10.11.13438
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !