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Proinflammatory Cytokines Provoke Oxidative Damage to Actin in Neuronal Cells Mediated by Rac1 and NADPH oxidase

The proinflammatory cytokines TNFα and Il-1β orchestrate the progression of CNS inflammation, which substantially contributes to neurodegeneration in many CNS pathologies. TNFα and Il-1β stimulate actin filament reorganization in non-neuronal cells often accompanied by the formation of reactive oxyg...

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Detalhes bibliográficos
Main Authors: Barth, Brian M., Stewart-Smeets, Shelli, Kuhn, Thomas B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2693287/
https://ncbi.nlm.nih.gov/pubmed/19344766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mcn.2009.03.007
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