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Neutral Sphingomyelinase Activation Precedes NADPH Oxidase-Dependent Damage in Neurons Exposed to the Proinflammatory Cytokine TNFα
Inflammation accompanied by severe oxidative stress plays a vital role in the orchestration and progression of neurodegeneration prevalent in chronic and acute CNS pathologies as well as in aging. The proinflammatory cytokine tumor necrosis factor alpha (TNFα) elicits the formation of the bioactive...
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| Autores principales: | , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2011
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3218197/ https://ncbi.nlm.nih.gov/pubmed/21932365 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jnr.22748 |
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