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Neutral Sphingomyelinase Activation Precedes NADPH Oxidase-Dependent Damage in Neurons Exposed to the Proinflammatory Cytokine TNFα

Inflammation accompanied by severe oxidative stress plays a vital role in the orchestration and progression of neurodegeneration prevalent in chronic and acute CNS pathologies as well as in aging. The proinflammatory cytokine tumor necrosis factor alpha (TNFα) elicits the formation of the bioactive...

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Main Authors: Barth, Brian M., Gustafson, Sally J., Kuhn, Thomas B.
格式: Artigo
語言:Inglês
出版: 2011
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3218197/
https://ncbi.nlm.nih.gov/pubmed/21932365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jnr.22748
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