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Gaucher’s Disease and Cancer: a Sphingolipid Perspective

Gaucher’s disease is a sphingolipidosis characterized by a specific deficiency in an acidic glucocerebrosidase, which results in aberrant accumulation of glucosylceramide primarily within the lysosome. Gaucher’s disease has been correlated with cases of myeloma, leukemia, glioblastoma, lung cancer,...

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Detalhes bibliográficos
Main Authors: Barth, Brian M., Shanmugavelandy, Sriram S., Tacelosky, Diana M., Kester, Mark, Morad, Samy A. F., Cabot, Myles C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3604879/
https://ncbi.nlm.nih.gov/pubmed/23510065
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