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Tamoxifen magnifies therapeutic impact of ceramide in human colorectal cancer cells independent of p53()

Poor prognosis in patients with later stage colorectal cancer (CRC) necessitates the search for new treatment strategies. Ceramide, because of its role in orchestrating death cascades in cancer cells, is a versatile alternative. Ceramide can be generated by exposure to chemotherapy or ionizing radia...

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Detalhes bibliográficos
Main Authors: Morad, Samy A.F., Madigan, James P., Levin, Jonathan C., Abdelmageed, Noha, Karimi, Ramin, Rosenberg, Daniel W., Kester, Mark, Shanmugavelandy, Sriram S., Cabot, Myles C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3604153/
https://ncbi.nlm.nih.gov/pubmed/23353700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2013.01.015
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