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Tamoxifen magnifies therapeutic impact of ceramide in human colorectal cancer cells independent of p53()

Poor prognosis in patients with later stage colorectal cancer (CRC) necessitates the search for new treatment strategies. Ceramide, because of its role in orchestrating death cascades in cancer cells, is a versatile alternative. Ceramide can be generated by exposure to chemotherapy or ionizing radia...

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Détails bibliographiques
Auteurs principaux: Morad, Samy A.F., Madigan, James P., Levin, Jonathan C., Abdelmageed, Noha, Karimi, Ramin, Rosenberg, Daniel W., Kester, Mark, Shanmugavelandy, Sriram S., Cabot, Myles C.
Format: Artigo
Langue:Inglês
Publié: 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3604153/
https://ncbi.nlm.nih.gov/pubmed/23353700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2013.01.015
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