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Structure of Mycobacterium tuberculosis thioredoxin in complex with quinol inhibitor PMX464
Thioredoxin (Trx) plays a critical role in the regulation of cellular redox homeostasis. Many disease causing pathogens rely on the Trx redox system for survival in conditions of environmental stress. The Trx redox system has been implicated in the resistance of Mycobacterium tuberculosis (Mtb) to p...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Wiley Subscription Services, Inc., A Wiley Company
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3047077/ https://ncbi.nlm.nih.gov/pubmed/20981751 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.533 |
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