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Structure of human thioredoxin exhibits a large conformational change

Thioredoxin is an oxidoreductase, which is ubiquitously present across phyla from humans to plants and bacteria. Thioredoxin reduces a variety of substrates through active site Cys 32, which is subsequently oxidized to form the intramolecular disulphide with Cys 35. The thioredoxin fold is known to...

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Detalhes bibliográficos
Main Authors: Hall, Gareth, Emsley, Jonas
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley Subscription Services, Inc., A Wiley Company 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2975144/
https://ncbi.nlm.nih.gov/pubmed/20661909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.466
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