تحميل...
Structures of 1-Deoxy-D-Xylulose-5-Phosphate Reductoisomerase/Lipophilic Phosphonate Complexes
[Image: see text] Fosmidomycin, a potent inhibitor of 1-deoxy-d-xylulose-5-phosphate reductoisomerase (DXR), has antibacterial and antimalaria activity. Due to its poor pharmacokinetics, more lipophilic DXR inhibitors are needed. However, the hydrophobic binding site(s) in DXR remains elusive. Here,...
محفوظ في:
| المؤلفون الرئيسيون: | , , , , , |
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| التنسيق: | Artigo |
| اللغة: | Inglês |
| منشور في: |
American Chemical Society
2010
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| الوصول للمادة أونلاين: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3046873/ https://ncbi.nlm.nih.gov/pubmed/21379374 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml100243r |
| الوسوم: |
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