Phosphodiesterase 4 Inhibition Reduces Innate Immunity and Improves Isoniazid Clearance of Mycobacterium tuberculosis in the Lungs of Infected Mice

Tuberculosis (TB) caused by Mycobacterium tuberculosis (Mtb) is one of the leading infectious disease causes of morbidity and mortality worldwide. Though current antibiotic regimens can cure the disease, treatment requires at least six months of drug therapy. One reason for the long duration of ther...

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Tallennettuna:
Bibliografiset tiedot
Päätekijät: Koo, Mi-Sun, Manca, Claudia, Yang, Guibin, O'Brien, Paul, Sung, Nackmoon, Tsenova, Liana, Subbian, Selvakumar, Fallows, Dorothy, Muller, George, Ehrt, Sabine, Kaplan, Gilla
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2011
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3045423/
https://ncbi.nlm.nih.gov/pubmed/21364878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0017091
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