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Pharmacologic Inhibition of Host Phosphodiesterase-4 Improves Isoniazid-Mediated Clearance of Mycobacterium tuberculosis

The lengthy duration of multidrug therapy needed to cure tuberculosis (TB) poses significant challenges for global control of the disease. Moreover, chronic inflammation associated with TB leads to pulmonary damage that can remain even after successful cure. Thus, there is a great need for the devel...

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Dades bibliogràfiques
Publicat a:Front Immunol
Autors principals: Subbian, Selvakumar, Koo, Mi-Sun, Tsenova, Liana, Khetani, Vikram, Zeldis, Jerome B., Fallows, Dorothy, Kaplan, Gilla
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4911353/
https://ncbi.nlm.nih.gov/pubmed/27379099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2016.00238
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