Phosphodiesterase-4 Inhibition Combined with Isoniazid Treatment of Rabbits with Pulmonary Tuberculosis Reduces Macrophage Activation and Lung Pathology

Tuberculosis (TB) is responsible for significant morbidity and mortality worldwide. Even after successful microbiological cure of TB, many patients are left with residual pulmonary damage that can lead to chronic respiratory impairment and greater risk of additional TB episodes due to reinfection wi...

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Main Authors: Subbian, Selvakumar, Tsenova, Liana, O'Brien, Paul, Yang, Guibin, Koo, Mi-Sun, Peixoto, Blas, Fallows, Dorothy, Zeldis, Jerome B., Muller, George, Kaplan, Gilla
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Investigative Pathology 2011
נושאים:
Regular Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3123788/
https://ncbi.nlm.nih.gov/pubmed/21703411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2011.03.039
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