Identification of Human IKK-2 Inhibitors of Natural Origin (Part I): Modeling of the IKK-2 Kinase Domain, Virtual Screening and Activity Assays

BACKGROUND: Their large scaffold diversity and properties, such as structural complexity and drug similarity, form the basis of claims that natural products are ideal starting points for drug design and development. Consequently, there has been great interest in determining whether such molecules sh...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Sala, Esther, Guasch, Laura, Iwaszkiewicz, Justyna, Mulero, Miquel, Salvadó, Maria-Josepa, Pinent, Montserrat, Zoete, Vincent, Grosdidier, Aurélien, Garcia-Vallvé, Santiago, Michielin, Olivier, Pujadas, Gerard
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2011
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3044726/
https://ncbi.nlm.nih.gov/pubmed/21390216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0016903
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires