Activation of Peroxisome Proliferator-Activated Receptor Gamma by Rosiglitazone Increases Sirt6 Expression and Ameliorates Hepatic Steatosis in Rats

BACKGROUND: Sirt6 has been implicated in the regulation of hepatic lipid metabolism and the development of hepatic steatosis. The aim of this study was to address the potential role of Sirt6 in the protective effects of rosiglitazone (RGZ) on hepatic steatosis. METHODS: To investigate the effect of...

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Main Authors: Yang, Soo Jin, Choi, Jung Mook, Chae, Seoung Wan, Kim, Won Jun, Park, Se Eun, Rhee, Eun Jung, Lee, Won Young, Oh, Ki Won, Park, Sung Woo, Kim, Sun Woo, Park, Cheol-Young
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2011
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3044155/
https://ncbi.nlm.nih.gov/pubmed/21373642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0017057
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