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Sirt1 and Sirt6 Mediate Beneficial Effects of Rosiglitazone on Hepatic Lipid Accumulation

BACKGROUND: Sirtuin (Sirt), a sensor of the cell metabolic state, regulates glucose and lipid metabolism. The aim of this study was to address whether rosiglitazone (RGZ) alters hepatic Sirt1 and whether Sirt1 and/or Sirt6 have a regulatory role in the protective effects of RGZ on hepatocyte steatos...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Yang, Soo Jin, Choi, Jung Mook, Chang, Eugene, Park, Sung Woo, Park, Cheol-Young
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2014
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4136882/
https://ncbi.nlm.nih.gov/pubmed/25133775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0105456
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