Ezetimibe improves hepatic steatosis in relation to autophagy in obese and diabetic rats

AIM: To investigate whether ezetimibe ameliorates hepatic steatosis and induces autophagy in a rat model of obesity and type 2 diabetes. METHODS: Male age-matched lean control LETO and obese and diabetic OLETF rats were administered either PBS or ezetimibe (10 mg/kg per day) via stomach gavage for 2...

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Pubblicato in:World J Gastroenterol
Autori principali: Chang, Eugene, Kim, Lisa, Park, Se Eun, Rhee, Eun-Jung, Lee, Won-Young, Oh, Ki-Won, Park, Sung-Woo, Park, Cheol-Young
Natura: Artigo
Lingua:Inglês
Pubblicazione: Baishideng Publishing Group Inc 2015
Soggetti:
Basic Study
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4491962/
https://ncbi.nlm.nih.gov/pubmed/26167075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v21.i25.7754
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