Exendin-4 Improves Steatohepatitis by Increasing Sirt1 Expression in High-Fat Diet-Induced Obese C57BL/6J Mice

The effects of exendin-4 on Sirt1 expression as a mechanism of reducing fatty liver have not been previously reported. Therefore, we investigated whether the beneficial effects of exendin-4 treatment on fatty liver are mediated via Sirt1 in high-fat (HF) diet-induced obese C57BL/6J mice and related...

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Détails bibliographiques
Auteurs principaux: Lee, Jinmi, Hong, Seok-Woo, Chae, Seoung Wan, Kim, Dong Hoon, Choi, Ji Hun, Bae, Ji Cheol, Park, Se Eun, Rhee, Eun-Jung, Park, Cheol-Young, Oh, Ki-Won, Park, Sung-Woo, Kim, Sun-Woo, Lee, Won-Young
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2012
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3281956/
https://ncbi.nlm.nih.gov/pubmed/22363635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0031394
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