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The critical role of GRP78 in physiologic and pathologic stress
GRP78 is a major endoplasmic reticulum chaperone as well as a master regulator of the unfolded protein response. In addition to playing an essential role in early embryonic development, recent studies have emerged specifically implicating GRP78 and chaperone integrity in the aging process and age-re...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3043145/ https://ncbi.nlm.nih.gov/pubmed/20970977 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ceb.2010.09.007 |
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