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Role of the Unfolded Protein Response, GRP78 and GRP94 in Organ Homeostasis

The endoplasmic reticulum (ER) is a cellular organelle where secretory and membrane proteins, as well as lipids, are synthesized and modified. When cells are subjected to ER stress, an adaptive mechanism referred to as the Unfolded Protein Response (UPR) is triggered to allow the cells to restore ho...

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Bibliographic Details
Published in:J Cell Physiol
Main Authors: ZHU, GENYUAN, LEE, AMY S.
Format: Artigo
Language:Inglês
Published: 2015
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4725317/
https://ncbi.nlm.nih.gov/pubmed/25546813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.24923
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