AKAP-Lbc enhances cyclic AMP control of the ERK1/2 cascade

Mitogen-activated protein kinase (MAPK) cascades propagate a variety of cellular activities1. Processive relay of signals through RAF–MEK–ERK modulates cell growth and proliferation2,3. Signalling through this ERK cascade is frequently amplified in cancers, and drugs such as sorafenib (which is pres...

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Detaylı Bibliyografya
Asıl Yazarlar: Smith, F. Donelson, Langeberg, Lorene K., Cellurale, Cristina, Pawson, Tony, Morrison, Deborah K., Davis, Roger J., Scott, John D.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2010
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3042953/
https://ncbi.nlm.nih.gov/pubmed/21102438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb2130
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