AKAP-Lbc mobilizes a cardiac hypertrophy signaling pathway

Elevated catecholamines in the heart evoke transcriptional activation of the Myocyte Enhancer Factor (MEF) pathway to induce a cellular response known as pathological myocardial hypertrophy. We have discovered that the A-Kinase Anchoring Protein AKAP-Lbc is up-regulated in hypertrophic cardiomyocyte...

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Main Authors: Carnegie, Graeme K., Soughayer, Joseph, Smith, F. Donelson, Pedroja, Benjamin S., Zhang, Fang, Diviani, Dario, Bristow, Michael R., Kunkel, Maya T., Newton, Alexandra C., Langeberg, Lorene K., Scott, John D.
Format: Artigo
Language:Inglês
Published: 2008
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3169907/
https://ncbi.nlm.nih.gov/pubmed/18951085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2008.08.030
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