The C-terminus of the long AKAP13 isoform (AKAP-Lbc) is critical for development of compensatory cardiac hypertrophy

The objective of this study was to determine the role of A-Kinase Anchoring Protein (AKAP)-Lbc in the development of heart failure, by investigating AKAP-Lbc-protein kinase D1 (PKD1) signaling in vivo in cardiac hypertrophy. Using a gene-trap mouse expressing a truncated version of AKAP-Lbc (due to...

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Detalhes bibliográficos
Main Authors: Taglieri, Domenico M., Johnson, Keven R., Burmeister, Brian T., Monasky, Michelle M., Spindler, Matthew J., DeSantiago, Jaime, Banach, Kathrin, Conklin, Bruce R., Carnegie, Graeme K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4074493/
https://ncbi.nlm.nih.gov/pubmed/24161911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2013.10.010
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