Genome-Wide Gene Expression Analysis Shows AKAP13-Mediated PKD1 Signaling Regulates the Transcriptional Response to Cardiac Hypertrophy

In the heart, scaffolding proteins such as A-Kinase Anchoring Proteins (AKAPs) play a crucial role in normal cellular function by serving as a signaling hub for multiple protein kinases including protein kinase D1 (PKD1). Under cardiac hypertrophic conditions AKAP13 anchored PKD1 activates the trans...

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Publicado en:PLoS One
Main Authors: Johnson, Keven R., Nicodemus-Johnson, Jessie, Spindler, Mathew J., Carnegie, Graeme K.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2015
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4508115/
https://ncbi.nlm.nih.gov/pubmed/26192751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0132474
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