The C-terminus of the long AKAP13 isoform (AKAP-Lbc) is critical for development of compensatory cardiac hypertrophy

The objective of this study was to determine the role of A-Kinase Anchoring Protein (AKAP)-Lbc in the development of heart failure, by investigating AKAP-Lbc-protein kinase D1 (PKD1) signaling in vivo in cardiac hypertrophy. Using a gene-trap mouse expressing a truncated version of AKAP-Lbc (due to...

Full description

Saved in:
Bibliographic Details
Main Authors: Taglieri, Domenico M., Johnson, Keven R., Burmeister, Brian T., Monasky, Michelle M., Spindler, Matthew J., DeSantiago, Jaime, Banach, Kathrin, Conklin, Bruce R., Carnegie, Graeme K.
Format: Artigo
Language:Inglês
Published: 2013
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4074493/
https://ncbi.nlm.nih.gov/pubmed/24161911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2013.10.010
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items