Cooperation between dE2F1 and Yki/Sd defines a distinct transcriptional program necessary to bypass cell cycle exit

The Hippo signaling pathway regulates organ size homeostasis, while its inactivation leads to severe hyperplasia in flies and mammals. The transcriptional coactivator Yorkie (Yki) mediates transcriptional output of the Hippo signaling. Yki lacks a DNA-binding domain and is recruited to its target pr...

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Autores principales: Nicolay, Brandon N., Bayarmagnai, Battuya, Islam, Abul B.M.M.K., Lopez-Bigas, Nuria, Frolov, Maxim V.
Formato: Artigo
Lenguaje:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2011
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3042156/
https://ncbi.nlm.nih.gov/pubmed/21325133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1999211
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