Loss of dE2F compromises mitochondrial function

E2F/DP transcription factors regulate cell proliferation and apoptosis. Here, we investigated the mechanism of the resistance of Drosophilad DP mutants to irradiation-induced apoptosis. Contrary to the prevailing view, this is not due to an inability to induce the apoptotic transcriptional program,...

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Bibliografische gegevens
Hoofdauteurs: Ambrus, Aaron M, Islam, Abul BMMK, Holmes, Katherine B., Moon, Nam Sung, Lopez-Bigas, Nuria, Benevolenskaya, Elizaveta V, Frolov, Maxim V
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2013
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3866969/
https://ncbi.nlm.nih.gov/pubmed/24286825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2013.10.002
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