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mir-11 limits the proapoptotic function of its host gene, dE2f1

The E2F family of transcription factors regulates the expression of both genes associated with cell proliferation and genes that regulate cell death. The net outcome is dependent on cellular context and tissue environment. The mir-11 gene is located in the last intron of the Drosophila E2F1 homolog...

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Autores principales: Truscott, Mary, Islam, Abul B.M.M.K., López-Bigas, Núria, Frolov, Maxim V.
Formato: Artigo
Lenguaje:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2011
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3175718/
https://ncbi.nlm.nih.gov/pubmed/21856777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.16947411
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