Cooperation between dE2F1 and Yki/Sd defines a distinct transcriptional program necessary to bypass cell cycle exit

The Hippo signaling pathway regulates organ size homeostasis, while its inactivation leads to severe hyperplasia in flies and mammals. The transcriptional coactivator Yorkie (Yki) mediates transcriptional output of the Hippo signaling. Yki lacks a DNA-binding domain and is recruited to its target pr...

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Bibliographic Details
Main Authors: Nicolay, Brandon N., Bayarmagnai, Battuya, Islam, Abul B.M.M.K., Lopez-Bigas, Nuria, Frolov, Maxim V.
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2011
Subjects:
Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3042156/
https://ncbi.nlm.nih.gov/pubmed/21325133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1999211
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