Cooperation between dE2F1 and Yki/Sd defines a distinct transcriptional program necessary to bypass cell cycle exit

The Hippo signaling pathway regulates organ size homeostasis, while its inactivation leads to severe hyperplasia in flies and mammals. The transcriptional coactivator Yorkie (Yki) mediates transcriptional output of the Hippo signaling. Yki lacks a DNA-binding domain and is recruited to its target pr...

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Autori principali: Nicolay, Brandon N., Bayarmagnai, Battuya, Islam, Abul B.M.M.K., Lopez-Bigas, Nuria, Frolov, Maxim V.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2011
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3042156/
https://ncbi.nlm.nih.gov/pubmed/21325133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1999211
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