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Novel regulation and functional interaction of polycistronic miRNAs

The importance of microRNAs in gene expression and disease is well recognized. However, what is less appreciated is that almost half of miRNA genes are organized in polycistronic clusters and are therefore coexpressed. The mir-11∼998 cluster consists of two miRNAs, miR-11 and miR-998. Here, we descr...

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Pubblicato in:RNA
Autori principali: Truscott, Mary, Islam, Abul B.M.M.K., Frolov, Maxim V.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4691827/
https://ncbi.nlm.nih.gov/pubmed/26554028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.053264.115
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