The Characterization of Microtubule-Stabilizing Drugs as Possible Therapeutic Agents for Alzheimer’s Disease and Related Tauopathies

Tau, a protein that is enriched in neurons of the central nervous system (CNS), is thought to play a critical role in the stabilization of microtubules (MTs). Several neurodegenerative disorders referred to as tauopathies, including Alzheimer’s disease and certain types of frontotemporal lobar degen...

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Hlavní autoři: Brunden, Kurt R., Yao, Yuemang, Potuzak, Justin S., Ferrer, Nuria Ibarz, Ballatore, Carlo, James, Michael J., Hogan, Anne-Marie L., Trojanowski, John Q., Smith, Amos B., Lee, Virginia M-Y.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3042036/
https://ncbi.nlm.nih.gov/pubmed/21163349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.phrs.2010.12.002
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