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2-Aminothiazoles as Therapeutic Leads for Prion Diseases
2-Aminothiazoles are a new class of small molecules with antiprion activity in prion-infected neuroblastoma cell lines.1 We report here structure-activity studies undertaken to improve the potency and physiochemical properties of 2-aminothiazoles, with a particular emphasis on achieving and sustaini...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2011
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3041857/ https://ncbi.nlm.nih.gov/pubmed/21247166 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm101250y |
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