Delivery of an EBV episome by a self-circularizing helper-dependent adenovirus: long-term transgene expression in immunocompetent mice

Epstein–Barr virus (EBV) evolved an episomal system for maintaining life-long, latent infection of human B lymphocytes. Circular episomes engineered from EBV components required for this latent form of infection have the capacity to persist in most types of replicating mammalian cells without DNA in...

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Hlavní autoři: Gil, JS, Gallaher, SD, Berk, AJ
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3041831/
https://ncbi.nlm.nih.gov/pubmed/20463755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gt.2010.75
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