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Helper-Dependent Adenovirus is Superior to First-Generation Adenovirus for Expressing Transgenes in Atherosclerosis-Prone Arteries
OBJECTIVE-: Vascular gene transfer is a powerful tool for investigating and treating vascular diseases; however, its utility is limited by brevity of transgene expression and vector-associated inflammation. Helper-dependent adenovirus (HDAd), an advanced-generation Ad that lacks all viral genes, is...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3098319/ https://ncbi.nlm.nih.gov/pubmed/21454808 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.111.225516 |
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