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Overexpression of Endothelial Nitric Oxide Synthase Improves Endothelium-Dependent Vasodilation in Arteries Infused with Helper-Dependent Adenovirus

Adenoviral vectors (Ad) are useful tools for in vivo gene transfer into endothelial cells. However, endothelium-dependent vasodilation is impaired after Ad infusion, and this impairment is not prevented by use of advanced-generation “helper-dependent” (HD) Ad that lack all viral genes. We hypothesiz...

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Detalhes bibliográficos
Main Authors: Jiang, Bo, Du, Liang, Flynn, Rowan, Dronadula, Nagadhara, Zhang, Jingwan, Kim, Francis, Dichek, David
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3498883/
https://ncbi.nlm.nih.gov/pubmed/22906141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2012.127
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