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Helper-Dependent Adenoviral Vector Achieves Prolonged, Stable Expression of Interleukin-10 in Rabbit Carotid Arteries but Does Not Limit Early Atherogenesis

Vascular gene therapy could potentially complement or replace current therapies for human atherosclerosis, while avoiding their side effects. However, development of vascular gene therapy is limited by lack of a useful vector. Helper-dependent adenovirus (HDAd) shows promise to overcome this barrier...

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Detalhes bibliográficos
Main Authors: Du, Liang, Dronadula, Nagadhara, Tanaka, Shinji, Dichek, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3159523/
https://ncbi.nlm.nih.gov/pubmed/21198399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2010.175
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