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Stable In Vivo Transgene Expression in Endothelial Cells with Helper-Dependent Adenovirus: Roles of Promoter and Interleukin-10

Our long-term goal is to prevent or reverse atherosclerosis by delivering gene therapy from stably transduced endothelial cells (EC). We previously reported that EC-directed gene therapy with a helper-dependent adenovirus (HDAd) expressing apolipoprotein A-I (apo A-I) retarded development of atheros...

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Detalhes bibliográficos
Publicado no:Hum Gene Ther
Main Authors: Dronadula, Nagadhara, Wacker, Bradley K., Van Der Kwast, Reginald, Zhang, Jingwan, Dichek, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5367915/
https://ncbi.nlm.nih.gov/pubmed/27842439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2016.134
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