Helper-dependent Adenoviral Vectors are Superior In Vitro to First-generation Vectors for Endothelial Cell-targeted Gene Therapy

Arterial endothelial cells (EC) are attractive targets for gene therapy of atherosclerosis because they are accessible to hematogenous and catheter-based vector delivery and overlie atherosclerotic plaques. Vector-mediated expression—in EC—of proteins that mediate cholesterol transfer out of the art...

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Bibliografski detalji
Glavni autori: Flynn, Rowan, Buckler, Joshua M, Tang, Chongren, Kim, Francis, Dichek, David A
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2010
Teme:
Original Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2997586/
https://ncbi.nlm.nih.gov/pubmed/20808287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2010.176
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