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Comparison of Replication-Competent, First Generation, and Helper-Dependent Adenoviral Vaccines
All studies using human serotype 5 Adenovirus (Ad) vectors must address two major obstacles: safety and the presence of pre-existing neutralizing antibodies. Helper-Dependent (HD) Ads have been proposed as alternative vectors for gene therapy and vaccine development because they have an improved saf...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2659436/ https://ncbi.nlm.nih.gov/pubmed/19333387 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0005059 |
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