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Comparison of Systemic and Mucosal Immunization with Helper-Dependent Adenoviruses for Vaccination against Mucosal Challenge with SHIV

Most HIV-1 infections are thought to occur at mucosal surfaces during sexual contact. It has been hypothesized that vaccines delivered at mucosal surfaces may mediate better protection against HIV-1 than vaccines that are delivered systemically. To test this, rhesus macaques were vaccinated by intra...

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Библиографические подробности
Главные авторы: Weaver, Eric A., Nehete, Pramod N., Nehete, Bharti P., Yang, Guojun, Buchl, Stephanie J., Hanley, Patrick W., Palmer, Donna, Montefiori, David C., Ferrari, Guido, Ng, Philip, Sastry, K. Jagannadha, Barry, Michael A.
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2013
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3701068/
https://ncbi.nlm.nih.gov/pubmed/23844034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0067574
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