Comparison of Systemic and Mucosal Immunization with Helper-Dependent Adenoviruses for Vaccination against Mucosal Challenge with SHIV

Most HIV-1 infections are thought to occur at mucosal surfaces during sexual contact. It has been hypothesized that vaccines delivered at mucosal surfaces may mediate better protection against HIV-1 than vaccines that are delivered systemically. To test this, rhesus macaques were vaccinated by intra...

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Détails bibliographiques
Auteurs principaux: Weaver, Eric A., Nehete, Pramod N., Nehete, Bharti P., Yang, Guojun, Buchl, Stephanie J., Hanley, Patrick W., Palmer, Donna, Montefiori, David C., Ferrari, Guido, Ng, Philip, Sastry, K. Jagannadha, Barry, Michael A.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2013
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3701068/
https://ncbi.nlm.nih.gov/pubmed/23844034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0067574
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