Effects of Stuffer DNA on Transgene Expression from Helper-Dependent Adenovirus Vectors

We have analyzed transgene (lacZ) expression from a first-generation adenovirus (Ad) vector in comparison to helper-dependent (hd) Ads deleted for various portions of the viral coding sequences and generated by using the Cre/loxP helper-dependent system (R. J. Parks et al., Proc. Natl. Acad. Sci. US...

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Bibliografiska uppgifter
Huvudupphovsmän: Parks, Robin J., Bramson, Jonathan L., Wan, Yonghong, Addison, Christina L., Graham, Frank L.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 1999
Ämnen:
Gene Therapy
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC112818/
https://ncbi.nlm.nih.gov/pubmed/10482551
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