Development of a Novel Helper-Dependent Adenovirus-Epstein-Barr Virus Hybrid System for the Stable Transformation of Mammalian Cells

Epstein-Barr virus (EBV) episomes are stably maintained in permissive proliferating cell lines due to EBV nuclear antigen 1 (EBNA-1) protein-mediated replication and segregation. Previous studies showed the ability of EBV episomes to confer long-term transgene expression and correct genetic defects...

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Main Authors: Dorigo, Oliver, Gil, Jose S., Gallaher, Sean D., Tan, Brenton T., Castro, Maria G., Lowenstein, Pedro R., Calos, Michele P., Berk, Arnold J.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology 2004
Ábhair:
Gene Therapy
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC416543/
https://ncbi.nlm.nih.gov/pubmed/15163748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.12.6556-6566.2004
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