Amyloid-beta alters trafficking of internalized acetylcholinesterase and dextran

Amyloid-beta (Aβ), the main peptide constituent of senile plaques, is a suspected pathogenic mediator in Alzheimer's Disease (AD). Plaques also contain acetylcholinesterase (AChE), which may promote Aβ toxicity. We previously found that Aβ increased AChE levels in neuron-like N1E.115 neuroblast...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Hu, William, Gray, Noah W, Brimijoin, Stephen
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: e-Century Publishing Corporation 2009
Gaiak:
Original Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3040938/
https://ncbi.nlm.nih.gov/pubmed/21383875
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