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Amyloid-beta alters trafficking of internalized acetylcholinesterase and dextran
Amyloid-beta (Aβ), the main peptide constituent of senile plaques, is a suspected pathogenic mediator in Alzheimer's Disease (AD). Plaques also contain acetylcholinesterase (AChE), which may promote Aβ toxicity. We previously found that Aβ increased AChE levels in neuron-like N1E.115 neuroblast...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
e-Century Publishing Corporation
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3040938/ https://ncbi.nlm.nih.gov/pubmed/21383875 |
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