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Interaction of amyloid beta with humanin and acetylcholinesterase is modulated by ATP

Humanin (HN) is known to bind amyloid beta (Aβ)‐inducing cytoprotective effects, while binding of acetylcholinesterase (AChE) to Aβ increases its aggregation and cytotoxicity. Previously, we showed that binding of HN to Aβ blocks aggregation induced by AChE and that HN decreases but does not abolish...

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Detalhes bibliográficos
Publicado no:FEBS Open Bio
Main Authors: Atali, Sarah, Dorandish, Sadaf, Devos, Jonathan, Williams, Asana, Price, Deanna, Taylor, Jaylen, Guthrie, Jeffrey, Heyl, Deborah, Evans, Hedeel Guy
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7714071/
https://ncbi.nlm.nih.gov/pubmed/33145964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/2211-5463.13023
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